Spatio-temporal characterization of phenotypic resistance in malaria vector species
Malaria, a deadly disease caused by Plasmodium protozoa parasite and transmitted through bites of infected female Anopheles mosquitoes, remains a significant public health challenge in sub-Saharan Africa. Efforts to eliminate malaria have increasingly focused on vector control using insecticides. However, the emergence of insecticide resistance (IR) in malaria vectors pose a formidable obstacle, and the current IR mapping models remain static, relying on fixed coefficients. This study introduces a dynamic spatio-temporal approach to characterize phenotypic resistance in Anopheles gambiae complex and Anopheles arabiensis.
Ibrahim EA, Wamalwa M, Odindi J, Tonnang HEZ. Spatio-temporal characterization of phenotypic resistance in malaria vector species. BMC Biol. 2024 May 20;22(1):117. doi: 10.1186/s12915-024-01915-z. PMID: 38764011; PMCID: PMC11102860.