CRISPR Cas9 mediated knockout of sex determination pathway genes in Aedes aegypti
Background
The vector role of Aedes aegypti for viral diseases including dengue and dengue hemorrhagic fever makes it imperative for its proper control. Despite various adopted control strategies, genetic control measures have been recently focused against this vector. CRISPR Cas9 system is a recent and most efficient gene editing tool to target the sex determination pathway genes in Ae. aegypti.
Zulhussnain, M., Zahoor, M. K., Ranian, K., Ahmad, A., & Jabeen, F. (2023). CRISPR Cas9 mediated knockout of sex determination pathway genes in Aedes aegypti. Bulletin of Entomological Research, 113(2), 243-252.